Phd theses georgoulia p (2012) computational studies of foldable tetra- and penta-peptides, phd thesis (pdf 10 mbytes) chatzisavvas a (2018) transition state identification via q-t diagrams : application to the cln025 peptide, diploma thesis (pdf 21 mbytes) chatzistylianou p (2017) folding of an amyloid. Award date: 27 september 2017 number of pages: 264 isbn: 978-94-6299-662 -5 document type: phd thesis faculty: faculty of medicine (amc-uva) abstract we describe the design and synthesis of a thin layer hydrogel with covalently attached synthetic antimicrobial peptides (amps) stabilized against proteolytic. Phd thesis, university of nottingham adams hill, rachel e (2016) computational studies of the dynamics and spectroscopy of peptides phd husseini, fouad (2017) computing the two-dimensional infrared spectra of proteins and small peptides using the exciton approach and molecular dynamics simulations phd. For her endless love, unlimited support and enormous encouragement when i encountered difficulties, felt depressed and lost strength also, i thank my families and hong's for their non-stopping support without them, none of my achievements would be possible this thesis, a product of my phd study, is dedicated to all of. Alan harris, phd thesis (uppsala university, uppsala, sweden) intranasal administration of peptides the effects of formulation and delivery systems on: nasal deposition, biological response and bioavailability of desmopressin defended in 1988 britt beding-barnekow, phd thesis (lund university, lund, sweden).
Congratulations to laura dietrich by grossmannlab on jul 25, 2017 laura successfully defended her phd thesis “zellgängige peptide zur inhibition des wnt/β-catenin signalwegs” eu research. Phd thesis of the university of cergy-pontoise immunological and conformational characterization of synthetic peptide probes for autoimmune diseases presented by : matthaia ieronymaki phd discussed on december 16th 2016 composition of the evaluation committee: pr paolo rovero examinateur. Peptide and nonpeptide approaches to target protein- protein interactions for the treatment of cancer by xu ran a dissertation submitted in partial fulfillment of the requirements for the degree of doctor of philosophy (medicinal chemistry) in the university of michigan 2015 doctoral.
Discovery and characterization of novel bioactive peptides from marine secondary products phd thesis by susan skanderup falkenberg february 28 th 2014. Phd thesis of the university of cergy-pontoise co-tutored with the university of florence non conventional synthetic strategies of stapled peptides: modulation of secondary structures to optimise biological recognition presented by : chiara testa phd discussed on march. Between the direct disruptive effects and the indirect immunomodulatory effects of the peptides this thesis also demonstrates that acps with a high cell membrane disruptive potential such as ltx-315 can be used in an immune augmenting adjuvant setting due to its potential to stimulate immune responses (paper iii.
The isolation of binders with optimal properties is highly dependent on the possibility to generate (bi)cyclic peptide libraries with high structural diversity and on the ability to thoroughly decode the phage selection output in my phd work, i developed new methods to generate large and structurally diverse. I would like to express my thanks to several people and institutions: first i express my heartiest gratitude to my supervisor of my phd thesis, professor ivar hordvik for his thorough guidence and enormous help for each and every progression in my phd project i extend thanks to all coauthors especially professor arnt. Doctoral thesis peptide conjugates containing chlorambucil or tetradentate aminopyridine ligands for anticancer treatment marta soler vives 2014 doctoral programme in chemistry supervised by: dr miquel costas salgueiro dr marta planas grabuleda dr lidia feliu soley tutor: dr anna roglans ribas.
On march 29 2018 olivier van der poorten obtained the academic degree of doctor of sciences with the following doctoral thesis: side chain constrained aromatic amino acids for use in peptide turn mimicry and cell-penetrating oligomers promotor: prof dr steven ballet read more. 21 juli 2017 antimicrobial peptides as new potential antibiotics reinhardt, andré (2017) antimicrobial peptides as new potential antibiotics phd thesis, universität zu köln. Peptide transport in the neonatal yucatan miniature pig nosworthy, matthew g ( 2015) peptide transport in the neonatal yucatan miniature pig doctoral (phd) thesis, memorial university of newfoundland. Doctoral dissertation synthesis of antimicrobial peptides derived from bp100 and bpc194 imma güell costa 2011 programa de doctorat en ciències experimentals i sostenibilitat phd supervisors: dra marta planas grabuleda dra lidia feliu soley memòria presentada per optar al títol de doctora per.
New generation recombinant antigenic peptides for vaccine and diagnostic antibody production phd student: santoni andrea tutor: prof simone ottonello co-ordinator: prof nelson the tdmi approach has been used, over the course of this thesis, to produce various antibodies against “problematic” antigens that. Development of a tert-butyl thiol linker for the synthesis of peptide thioesters and thioacids for application in chemical ligation methods inaugural- dissertation to obtain the academic degree doctor rerum naturalium (dr rer nat ) the faculty of chemie, biologie, pharmazie freie universität berlin may 2011. A thesis submitted in partial fulfilment of the requirements of the of doctor of philosophy faculty of health, psychology and social care the manchester metropolitan university in collaboration with manchester royal infirmary june 2014 phd 2014 386 106 appendix vi – characteristics of the natriuretic peptides.
Drug from its carrier  examples for in vitro and in vivo efficacy of rgd-targeted therapeutics and diagnostics demonstrate the value of rgd-mediated drug targeting in this thesis i developed novel αvβ3-integrin-targeted conjugates consisting of cyclic rgd- peptides as targeting moiety, different drugs, and human serum. Antimicrobial peptide mechanisms antibiotic resistance is increasing at an alarming rate life depends on the integrity of biological membranes and their ability to maintain function disrupting bacterial but not mammalian membrane integrity with peptides is an alternate strategy to destroy toxic bacteria mechanisms of amp. 1 huhtikuu 2016 title: mesoporous silicon systems for oral protein/peptide-based diabetes mellitus therapy author: shrestha, neha contributor: university of helsinki, faculty of pharmacy, division of pharmaceutical chemistry and technology thesis level: doctoral dissertation (article-based) belongs to series.